Figure 3
SW480 and LoVo cells as well as IEC cells were plated at 105 cells per 6 cm dishes and infected with ZD55-Sur-EGFP (A) or AD-Sur-EGFP (B) for 48 h (a) or 72 h (b). Then the cells were observed through a fluorescence microscope. ZD55-Sur-EGFP showed much stronger affinity to SW480 cells than AD-Sur-EGFP, but it rarely replicated in normal cells IEC at 24 h post infection. After 72 h, the cells infected with ZD55-Sur-EGFP became lysed but there was little change in the morphology of AD-Sur-EGFP infected cells. (Original magnification ×200).