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Figure 8 | Journal of Experimental & Clinical Cancer Research

Figure 8

From: Oncolytic adenovirus mediated Survivin knockdown by RNA interference suppresses human colorectal carcinoma growth in vitro and in vivo

Figure 8

Effect of adenoviruses on caspase-3 activity in SW480 and LoVo cells. Western blot analysis was performed 48 h post infection. The activation of caspase-3 (demonstrated as increased expression of cleaved fragments of caspase-3) was more obvious in ZD455-Sur-EGFP group (D) than in AD-Sur-EGFP group (C), whereas AD-EGFP (A) and ZD55-EGFP (B) did not actvivate caspase-3.

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