Table 5 Univariate and Multivariate analyses of factors associated with survival after resection in patients with pancreatic cancer.
From: Prognostic value of metastin expression in human pancreatic cancer
| Â | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
Characteristics | Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value |
Age (continuous variables) | 1.01 (0.97–1.1) | 0.50 | 1.03 (0.97–1.1) | 0.29 |
Gender (male versus female) | 1.09 (0.73–1.6) | 0.66 | 1.16 (0.73–1.9) | 0.52 |
Location of tumor (head versus body-tail) | 1.08 (0.72–1.7) | 0.72 | 0.71 (0.40–1.3) | 0.25 |
Size of tumor (continuous variables) | 1.01 (0.97–1.0) | 0.63 | 1.01 (0.96–1.1) | 0.69 |
Histopathological grading (G1 versus G2-4) | 1.05 (0.70–1.7) | 0.80 | 0.92 (0.49–1.8) | 0.79 |
pT (pT1, pT2 versus pT3) | 1.62 (0.88–4.0) | 0.14 | 2.07 (0.86–6.7) | 0.11 |
pN (pN0 versus pN1) | 1.27 (0.85–2.0) | 0.25 | 1.01 (0.58–1.8) | 0.97 |
Lymphatic invasion (positive versus negative) | 1.20 (0.80–1.8) | 0.33 | 0.97 (0.54–1.7) | 0.92 |
Venous invasion (positive versus negative) | 1.01 (0.68–1.5) | 0.95 | 0.91 (0.52–1.6) | 0.73 |
Perineural invasion (positive versus negative) | 1.57 (1.1–2.4) | 0.03 | 1.47 (0.85–2.7) | 0.17 |
pStage (I, II versus IV) | 3.16 (1.6–5.8) | 0.002 | 2.70 (1.1–6.8) | 0.03 |
Residual tumor (R0 versus R1) | 1.61 (1.0–2.5) | 0.03 | 1.60 (0.91–2.9) | 0.10 |
Metastin expression (positive versus negative) | 1.93 (1.1–4.0) | 0.01 | 2.08 (1.1–4.7) | 0.03 |
GPR54 expression (positive versus negative) | 1.62 (1.1–2.5) | 0.02 | 1.22 (0.74–2.0) | 0.43 |