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Table 1 The association between XRCC1 polymorphisms at codons 194 and 399 and NAC response in locally advanced cervical carcinoma

From: The association of XRCC1gene single nucleotide polymorphisms with response to neoadjuvant chemotherapy in locally advanced cervical carcinoma

XRCC1 genotype N Good response
[N (%)]
Poor response
[N (%)]
OR 95%CI
Codon 194
Arg/Arg
34 28 (82.35) 6 (17.65)   
   Arg/Trp 24 24 (100) 0 (0)   
   Trp/Trp 12 8 (66.67) 4 (33.33) 2.333 0.52~10.35
   Arg/Trp+ Trp/Trp 36 32 (88.89) 4 (11.11) 0.583* 0.14~2.28
Codon 399
Arg/Arg
44 40(90.90) 4 (9.10)   
   Arg/Gln 2 0 (0) 2 (100)   
   Gln/Gln 24 20 (83.33) 4 (16.67) 2.000 0.452 ~8.842
   Arg/Gln+ Gln/Gln 26 20 (76.92) 6 (23.08) 3.254** 1.708 ~ 14.951
  1. Good response: CR+PR; Poor response: SD+PD; OR: odds ratio
  2. *: Arg/Trp+Trp/Trp vs Arg/Arg; **: Arg/Gln+Gln/Gln vs Arg/Arg