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Table 1 The association between XRCC1 polymorphisms at codons 194 and 399 and NAC response in locally advanced cervical carcinoma

From: The association of XRCC1gene single nucleotide polymorphisms with response to neoadjuvant chemotherapy in locally advanced cervical carcinoma

XRCC1 genotype

N

Good response

[N (%)]

Poor response

[N (%)]

OR

95%CI

Codon 194

Arg/Arg

34

28 (82.35)

6 (17.65)

  

   Arg/Trp

24

24 (100)

0 (0)

  

   Trp/Trp

12

8 (66.67)

4 (33.33)

2.333

0.52~10.35

   Arg/Trp+ Trp/Trp

36

32 (88.89)

4 (11.11)

0.583*

0.14~2.28

Codon 399

Arg/Arg

44

40(90.90)

4 (9.10)

  

   Arg/Gln

2

0 (0)

2 (100)

  

   Gln/Gln

24

20 (83.33)

4 (16.67)

2.000

0.452 ~8.842

   Arg/Gln+ Gln/Gln

26

20 (76.92)

6 (23.08)

3.254**

1.708 ~ 14.951

  1. Good response: CR+PR; Poor response: SD+PD; OR: odds ratio
  2. *: Arg/Trp+Trp/Trp vs Arg/Arg; **: Arg/Gln+Gln/Gln vs Arg/Arg