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Table 2 Fold changes in apoptosis related genes by OligoArray in OVCAR-3 cells

From: Enhancing cytotoxic and apoptotic effect in OVCAR-3 and MDAH-2774 cells with all-trans retinoic acid and zoledronic acid: a paradigm of synergistic molecular targeting treatment for ovarian cancer

 

Fold Change in OVCAR-3 cells

Gene Symbol

ATRA

(80 nM)

Zoledronic Acid

(5 μM)

Combination

BCL2L-1 (BCL-xL)

-1.8

-2.1

-4.0

BCL2L12

-1.3

-1.5

-3.1

BCL2L13

-1.3

-2.6

-7.0

BNIP3

+1.9

+2.4

+3.9

TNFRSF1A

+1.5

+3.6

+6.8

TNFRSF10B

+1.6

+3.4

+4.9

TRADD

+1.3

+1.2

+4.8

CASP4

+1.2

+1.4

+3.2

MCL-1

-2.2

-1.6

-3.3

BAG3

-1.0

-1.0

-3.1

LTBR

-1.4

+2.5

-4.9

  1. *p < 0.05