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Table 3 The relationship between the expression of BCL-2, BAD and the histologic grade, clinical TNM stages and the axillary lymph nodes metastasis in youth and menopause breast cancer tissues

From: Expression of the apoptosis-related genes BCL-2 and BAD in human breast carcinoma and their associated relationship with chemosensitivity

 

Total

Histologic grade

Clinical TNM stage

Axillary lymph nodes

  

I

II

III

I

II

III

IV

Positive

Negative

Youth breast cancer tissues

40

8

27

5

6

25

8

1

19

21

BCL-2+

19

7

12

0

4

12

3

0

3

16

BCL-2-

21

1

15

5

2

13

5

1

16

5

+%

47.5%

87.5%1

44.4%

0.0%

66.7%3

48.0%

37.5%

0.0%

15.8%4

76..2%

BAD+

12

4

8

0

2

8

2

0

6

6

BAD-

28

4

19

5

4

17

6

1

13

15

+%

30.0%

50.0%2

29.6%

0.0%

33.3%3

32.0%

25.0%

0.0%

31.6%5

28.6%

Menopause breast cancer tissues

40

18

19

3

5

22

11

2

10

30

BCL-2+

30

16

14

0

4

17

8

1

2

28

BCL-2-

10

2

5

3

1

5

3

1

8

2

+%

75.0%

88.9%2

73.7%

0.0%

80.0%3

77.3%

72.7%

50.0%

20.0%4

93.3%

BAD+

25

11

13

1

4

15

6

0

5

20

BAD-

15

7

6

2

1

7

5

2

5

10

+%

62.5%

61.1%2

68.4%

33.3%

80.0%3

68.2%

54.5%

0.0%

50.0%5

66.7%

  1. Compare with each other in the same group:1: P < 0.01,2: P > 0.05,3: P > 0.05,4: P < 0.01,5: P > 0.05