Figure 2From: A mouse model for the Sézary syndromeMorphology of an excised tumor from CB-17 SCID beige mice. A) Overview. The center of the tumor with necrotic cells is on the bottom on the right side of the figure. The area of living tumor cells can be recognized by the staining with the FLIP antibody. Tumor associated blood vessels appear as white holes. Tumor cells infiltrate the dermis and the epidermis is still intact. Note that the cells at the bottoms of the hair follicles also stain strongly with the FLIP antibody. B) Presence of malignant T cells in the tumor area proven by staining with a CD3 antibody. C) FLIP antibody staining of granulocytes. The FLIP staining cells show the typical segmented nuclei of granulocytes. The original magnifications of the figures 2A, 2B, and 2C were 5×, 20×, and 50× respectively.Back to article page