Table 3 Gene ontology of the 20-gene signature

D43950

KIAA0098

Protein folding/Response to virus

U96131

TRIP13

Double stranded break DNA repair/Meosis I/Spermatogonial Development/Oocyte maturation/Pachytene (cell cycle)/Meotic recombination/Transcription from RNA Pol II promoter

NM_014865

KIAA0159

N/A

Contig55725_RC

N/A

AF047002

ALY

Interspecies interaction between organisms/Intronless viral mRNA export from nucleus/mRNA export from nucleus/mRNA processing/Transport

NM_004111

FEN1

DNA repair/DNA replication/Double stranded break DNA repair/UV protection/Phosphoinositide mediated signaling

NM_004153

ORC1L

DNA replication/DNA dependent DNA replication

NM_004631

LRP8

Cytokine mediated signaling pathway/Endocytosis/Hippocampus development/Layer formation in the cerebral cortex/Lipid metabolic process/Positive regulation of kinase activity/Proteolysis/Signal transduction

NM_002794

PSMB2

Anaphase-promoting complex-dependent proteosomal ubiquitin dependent protein catabolic process/Interspecies interaction between organisms/Negative regulation of ubiquitin ligase activity involved in mitotic cell entry/Positive regulation of ubiquitin ligase activity involved in mitotic cell entry/Proteolysis involved in cellular protein catabolic process

Contig55771_RC

N/A

NM_004496

HNF3A

Branching morphogenesis of a tube/Chromatin remodelling/Epithelial cell differentiation/Prostate gland development/Glucose homeostasis/Hormone metabolic process/Lung development/Multicellular organismal development/Negative regulation of survival gene product/Negative regulation of transcription fro RNA pol II promoter/Neuron fate specification

NM_006113

VAV3

Angiogenesis/Apoptosis/Cell Migration/Induction of apoptosis by extracellular signals/Integrin mediated signaling pathway/Lamellipodium assembly/Positive regulation of cell adhesion/Positive regulation of PI3 kinase activity/Regulation of GTPase activity/Regulation of Rho protein signal transduction/Small GTPase mediated signal transduction/Vesicle fusion

AL161983

Regulation of translation/Translation initiation

NM_016613

LOC51313

N/A

AL133074

Apoptosis/Cell cycle arrest/Induction of apoptosis/Response to stress

Contig14284_RC

N/A

Contig56678_RC

N/A

NM_000125

ESR1

Androgen metabolic process/Antral ovarian follicle growth/Epithelial cell development/Epithelial cell proliferation involved in mammary gland duct elongation/Estrogen receptor signaling pathway/Male gonad development/Mammary gland alveolus development/Mammary gland branching involved in pregnancy/Neuroprotection/Osteoblast development

Contig57480_RC

N/A

NM_005113

GOLGA5

Golgi organisation/Golgi vesicle transport/Protein amino acid phosphorylation/Retrograde transport, vesicle recycling within golgi