Expression and clinical significance of multidrug resistance proteins in brain tumors

Table 1 Expression of the 5 multidrug resistance proteins in the tumor cells

Multidrug resistance protein	n	-	+	++	Strongly positive rate (%)
P-gp	30	4	18	8	26.67
Topo II	30	13	10	7	23.33
GST-π	30	10	15	5	16.67
MRP	30	28	1	1	3.33
LRP	30	26	3	1	3.33

In tumor cells, the strongly positive rate of P-gp, Topo II, GST-π, LRP and MRP were 26.67%,23.33%,16.67%,3.33% and 3.33%, respectively. This difference was statistically significant (Rank sum test, P < 0.05)

ISSN: 1756-9966