Expression and clinical significance of multidrug resistance proteins in brain tumors

Table 2 Expression of the 5 multidrug resistance proteins in the capillary walls of tumor tissues

Multidrug resistance protein	n	-	+	++	+++	Strongly positive rate (%)
P-gp	30	3	6	12	9	70.00
Topo II	30	23	5	2	0	6.67
GST-π	30	26	3	1	0	3.33
MRP	30	27	2	1	0	3.33
LRP	30	27	3	0	0	0.00

The expression of P-gp is strongly positive in capillary vessels. Low positive expression of LRP, MRP, GST-π and Topo II was observed in capillary vessels. This difference was statistically significant (Rank sum test, P < 0.01)

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