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Table 4 Positive expression of the 5 multidrug resistance proteins in the different grades of brain tumors

From: Expression and clinical significance of multidrug resistance proteins in brain tumors

Multidrug resistance proteins Tumor cells Capillary vessels Interstitial cells
  H L P H L P H L P
n 10 20 - 10 20 - 10 20 -
P-gp 4 3 0.378 6 2 0.027 8 19 0.251
Popo 4 4 0.384 0 0 - 0 0 -
GST 3 2 0.3 0 0 - 8 14 0.682
MRP 0 0 - 0 0 - 2 2 0.584
LRP 0 0 - 0 0 - 2 2 0.584
  1. In tumor cells and interstitial cells, there was no significant difference between the expression of the 5 multidrug resistance proteins (Fisher definite probability methods, P > 0.05) between high grade and low grade tumors. In the capillary vessels, the strong positive expression of P-gp was 60% (6/10) in high grade and 10% (2/20) in low grade tumors. This difference was statistically significant (Fisher definite probability methods, P < 0.05).