Figure 1

EGFR CISH analysis on non small cell lung carcinoma. Two different patterns of gene and chromosome 7 copy number obtained by CISH on cell blocks prepared from two different Lung Carcinoma FNAC: (A) EGFR not amplified and (B) paired chromosome 7 disomy; (C) EGFR gene amplification with a clustered pattern and (D) trisomy of chromosome 7. Original magnification ×1000.