Chromogenic in situ hybridization to detect EGFR gene copy number in cell blocks from fine-needle aspirates of non small cell lung carcinomas and lung metastases from colo-rectal cancer

Table 1 Distribution of EGFR gene copy number evaluated by CISH according to tumor histotype

Histotype	N° of cases	Disomy	Trisomy	Polysomy	Amplified
ADC	7	1	2	3	1
LCC	8	2	1	4	1
SCC	5	1	3	1	0
mCRC	13	2	4	7	0
Total	33	6	10	15	2

ADC: adenocarcinoma; LCC: large cell carcinoma; SCC: squamous cell carcinoma; mCRC: metastatic colo-rectal cancer; Disomy: 1.6-2.0 balanced gene and chromosome 7; Trisomy: balanced 2.2-3.0 gene and chromosome 7; Polysomy: 3.1-4.4 balanced gene and chromosome 7; Amplified: gene-to-chromosome 7 ratio ≥ 2

ISSN: 1756-9966