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Table 3 SNP sites showing frequency difference between HCC and control.

From: Identification of sequence polymorphism in the D-Loop region of mitochondrial DNA as a risk factor for hepatocellular carcinoma with distinct etiology

Nucleotidea

Control

HBV-HCC

Alcohol-HCC

Trend-p valueb

16266 C/T

37/1 (2.6)c

49/0 (0.0)

8/2 (20.0)

0.0038 d

P value

 

0.4368

0.1058

 

16293 A/G

38/0 (0.0)

48/1 (2.0)

8/2 (20.0)

0.0042

P value

 

>0.9999

0.0399

 

16298 T/C

35/3 (7.9)

37/12 (24.5)

9/1 (10.0)

0.0992

P value

 

0.0495

>0.9999

 

16299A/G

38/0 (0.0)

49/0 (0.0)

9/1 (10.0)

0.0123

P value

 

>0.9999

0.2083

 

16303 G/A

38/0 (0.0)

49/0 (0.0)

9/1 (10.0)

0.0123

P value

 

>0.9999

0.2083

 

152 T/C

30/8 (21.1)

31/18 (36.7)

10/0 (0.0)

0.0340

P value

 

0.1130

0.1767

 

242 C/T

38/0 (0.0)

49/0 (0.0)

9/1 (10.0)

0.0123

P value

 

>0.9999

0.2083

 

368 A/G

38/0 (0.0)

49/0 (0.0)

9/1 (10.0)

0.0123

P value

 

>0.9999

0.2083

 

462 C/T

38/0 (0.0)

49/0 (0.0)

9/1 (10.0)

0.0123

P value

 

>0.9999

0.2083

 

523 A/del

32/6 (15.8)

31/18 (36.7)

4/6 (60.0)

0.0122

P value

 

0.0302

0.0092

 

525C/del

30/8 (21.1)

31/18 (36.7)

4/6 (60.0)

0.0483

P value

 

0.1130

0.0447

 
  1. aFisher's exact test: HCC vs. control.
  2. bChi-square test for trend.
  3. cNumber in parenthesis: SNP percentage.
  4. dNumber in bold: p < 0.05.