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Table 3 SNP sites showing frequency difference between HCC and control.

From: Identification of sequence polymorphism in the D-Loop region of mitochondrial DNA as a risk factor for hepatocellular carcinoma with distinct etiology

Nucleotidea Control HBV-HCC Alcohol-HCC Trend-p valueb
16266 C/T 37/1 (2.6)c 49/0 (0.0) 8/2 (20.0) 0.0038 d
P value   0.4368 0.1058  
16293 A/G 38/0 (0.0) 48/1 (2.0) 8/2 (20.0) 0.0042
P value   >0.9999 0.0399  
16298 T/C 35/3 (7.9) 37/12 (24.5) 9/1 (10.0) 0.0992
P value   0.0495 >0.9999  
16299A/G 38/0 (0.0) 49/0 (0.0) 9/1 (10.0) 0.0123
P value   >0.9999 0.2083  
16303 G/A 38/0 (0.0) 49/0 (0.0) 9/1 (10.0) 0.0123
P value   >0.9999 0.2083  
152 T/C 30/8 (21.1) 31/18 (36.7) 10/0 (0.0) 0.0340
P value   0.1130 0.1767  
242 C/T 38/0 (0.0) 49/0 (0.0) 9/1 (10.0) 0.0123
P value   >0.9999 0.2083  
368 A/G 38/0 (0.0) 49/0 (0.0) 9/1 (10.0) 0.0123
P value   >0.9999 0.2083  
462 C/T 38/0 (0.0) 49/0 (0.0) 9/1 (10.0) 0.0123
P value   >0.9999 0.2083  
523 A/del 32/6 (15.8) 31/18 (36.7) 4/6 (60.0) 0.0122
P value   0.0302 0.0092  
525C/del 30/8 (21.1) 31/18 (36.7) 4/6 (60.0) 0.0483
P value   0.1130 0.0447  
  1. aFisher's exact test: HCC vs. control.
  2. bChi-square test for trend.
  3. cNumber in parenthesis: SNP percentage.
  4. dNumber in bold: p < 0.05.