Skip to main content

Table 4 Comparison of SNP frequencies with different 489 status among subject groups.

From: Identification of sequence polymorphism in the D-Loop region of mitochondrial DNA as a risk factor for hepatocellular carcinoma with distinct etiology

SNPs Control (n = 38) HBV-HCC (n = 49) Alcohol-HCC (n = 11) P valued
489T/152T 19 (50.0)c 13 (26.5) 3 (27.3) >0.9999
P value   0.0243 0.3028  
489C/152T 11 (28.9) 18 (36.7) 8 (72.7) 0.0437
P value   0.4447 0.0139  
489C/249A 13 (34.2) 19 (38.8) 8 (72.7) 0.0513
P value   0.6614 0.0372  
489C/309C 6 (15.8) 12 (24.5) 6 (54.5) 0.0706
P value   0.3204 0.0158  
489T/523A 19 (50.0) 11 (22.4) 3 (27.3) 0.7075
P value   0.0073 0.3028  
489C/523Del 2 (5.3) 6 (12.2) 6 (54.5) 0.0051
P value   0.4571 0.0007  
489T/525C 18 (47.4) 10 (20.4) 3 (27.3) 0.6899
P value   0.0076 0.3106  
489C/525Del 3 (7.9) 6 (12.2) 6 (54.5) 0.0051
P value   0.7256 0.0020  
  1. aHCC vs. control (Number/patient: unpaired T test; SNP-defined haplotypes: Fisher's Exact test, otherwise chi-square analysis to obtain values in italic).
  2. bMean ± standard deviation.
  3. cNumber in parenthesis: percentage.
  4. dHBV-HCC vs. Alcohol-HCC.