Skip to main content

Table 3 EGFR mutations found in the NSCLC samples using a combination of DNA sequencing and ARMS.

From: A comparison of ARMS and DNA sequencing for mutation analysis in clinical biopsy samples

Mutation No. of mutations Detected by ARMS* Detected by sequencing
del E746-A750 9 9 4
del E749-E758insQP 1 ND 1
del L747-P753 ins Q 1* ND 1
del E749-A753 ins P 1 ND 1
del L747-P753 ins S 1 ND 1
Other deletions 1 ND 1
G719A 1 ND 1
A743S 1 ND 1
L858R 9* 9 4
L861Q 2 ND 2
Total 27 18 17
  1. EGFR-2 kit detecting L858R and del E746-A750 only. Other mutations not detectable by this version of the kit.
  2. *One patient had both an exon 19 deletion and an L858R point mutation.ND, not detectable.