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Table 1 Studies using radiation therapy rat model in combination with anticancer therapeutic agents

From: External irradiation models for intracranial 9L glioma studies

Studies

Target

Tumor Cell line

Total dose

Number of fractions

Survival

Roullin VG (6)

HB

C6

36 Gy

9

Complete response : 8%

Graf MR (7)

WB

T9

15 Gy

1

35 days (median)

Kimler BF (8)

WB

9L

20 Gy

1

S

   

30 Gy

5

S

Kimler BF (9)

WB

9L

40-70 Gy

10-20

S

Kimler BF (10)

WB

9L

16 Gy

1

38.5 days (mean)

Kimler BF (11)

WB

9L

16 Gy

1

S

   

24 Gy

1

S

   

32 Gy

1

S

   

40 Gy

1

S

Lamproglou I (12)

WB

-

30 Gy

10

-

Olson JJ (13)

WB

9L

30 Gy

1

29.7 days (mean)

  1. WB: Whole brain/HB: Hemibrain/S: Significant
  2. NB: Lamproglou worked on normal rat brains.