Figure 1

Oncomine database shows significant SOSTDC1 downregulation in adult renal clear cell tumors and pediatric Wilms tumors. The Oncomine database was queried for all studies involving markers in SOSTDC1 (data queried on 11/08/2010). Results of five studies were compared using the software available on the site [40–44]. Dots above and below the boxes show sample maximum and minimum values, respectively. The horizontal lines show the spread of the values from starting at the 10% value through the 90% value, with the box highlighting the range of 25% to 75%. Dark boxes show the normal or control tissues for each study and white boxes show adult clear cell renal carcinoma and Wilms tumor values. The horizontal black bar through each box shows the median value for the sample. ** p < 0.001, normal adult or fetal renal tissue compared to adult RCC or Wilms tumors.