Rapamycin augments Dex's growth inhibition on T-ALL cell lines. (A) Four T-ALL cell lines (CEM-C7-14, CEM-C1-15, Molt-4, and Jurkat) were incubated for 48 h with rapamycin (10 nM) and/or Dex (1 μM), and the proliferation rate of the cells were evaluated by MTT assay. (B) GC-resistant cell line Jurkat was exposed for 72 h to rapamycin (10 nM) and Dex (1 μM) alone or in combination. At time 0, 24, 48 and 72 h after treatment, proliferation rate of the cells were evaluated by MTT assay. For each assay, values of triple experiments were shown as mean plus or minus SD. * p < 0.05 as compared with control group or Rap group or Dex group.