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Table 4 Main toxicity results for lipiodol TACE and pTACE according to NCI-CTC 3.0 (National Cancer Institute - Common Toxicity Criteria 3.0).

From: Trans-arterial chemo-embolization (TACE), with either lipiodol (traditional TACE) or drug-eluting microspheres (precision TACE, pTACE) in the treatment of hepatocellular carcinoma: efficacy and safety results from a large mono-institutional analysis

Toxicity

        
 

Total

G3 - G4

 

TACE lipiodol

pTACE microspheres

TACE lipiodol

pTACE microspheres

 

early

late

early

late

early

late

early

late

Hepatic (%)

        

transaminase

31 (41)

6 (8)

22 (33)

11 (16)

7 (9)

-

2 (3)

-

γ-gt

22 (29)

9 (12)

16 (24)

12 (18)

5 (7)

3 (4)

5 (7)

6 (9)

alkaline phosphatase

8 (11)

4 (5)

7 (10)

7 (10)

-

-

-

-

bilirubin

25 (33)

2 (3)

16 (24)

5 (7)

3 (4)

2 (3)

3 (4)

-

coagulation

-

1 (1)

-

-

-

-

-

-

albumin

7 (9)

2 (3)

3 (4)

1 (1)

-

-

1 (1)

-

Hematologic (%)

        

leukopenia

4 (5)

2 (3)

2 (3)

4 (6)

1 (1)

-

1 (1)

1 (1)

anemia

8 (11)

6 (8)

6 (9)

4 (6)

1 (1)

-

-

-

piastinopenia

22 (29)

6 (8)

21 (31)

11 (16)

1 (1)

-

6 (9)

2 (3)

Other (%)

        
 

pain

2 (5)

-

8 (23)

-

-

-5 (14)

 
 

fever

2 (5)

1 (3)

3 (9)

-

-

-

-