Figure 3From: All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax proteinATRA affects on the expression of survivin and Bax. Panel A shows the down-regulated expression of survivin after 2-, 4- or 6-day treatment with 180 μM ATRA. Panel B shows the up-regulated expression of Bax after 2-, 4- or 6-day treatment with 180 μM ATRA. Panel C shows the effect of ATRA on XIAP expression after 2-, 4- or 6-day treatment with 180 μM ATRA.Back to article page