Figure 5From: All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax proteinPanel A shows the result of scratch assay, GIST-T1 cells were treated with or without ATRA (90 μM). Migration was observed after 24-hour incubation. Panel B shows the isobologram result of drug combination between ATRA and imatinib. This combination resulted in additive effect.Back to article page