Figure 1
Inhibition of tumor growth in Rag2-/-; γcommon -/- male mice injected s.c. with GIST 882 by treatment p.o. with untreated (-□-), imatinib (-◊-), everolimus (⋯○⋯), imatinib+everolimus (-♦-), nilotinib (⋯●⋯), nilotinib+imatinib (--▼-). The dotted line marks the beginning of therapy. The tumor volumes are expressed as mean ± E.S in cm3. §p > 0.01, *p < 0.05, Student's t test compared with untreated group.