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Table 2 Meta-analysis results of C282Y polymorphism and HCC

From: Association between C282Y and H63D mutations of the HFE gene with hepatocellular carcinoma in European populations: a meta-analysis

 

Nine studies of all samples

Seven studies of healthy controls

Four studies of alcoholic LC

Four studies of viral LC

Genetic model

Dominant

Allele contrast

CY vs. CC

Dominant

Allele contrast

Dominant

Allele contrast

Dominant

Allele contrast

OR

1.43

1.50

1.31

1.46

1.61

4.06

3.41

0.70

0.71

95%CI

0.98-2.07

1.05-2.14

0.89-1.95

0.96-2.22

1.08-2.39

2.08-7.92

1.81-6.41

0.32-1.50

0.34-1.50

p for hetero

0.02

0.02

0.02

0.04

0.04

0.77

0.47

0.47

0.49

I2

0.55

0.57

0.56

0.54

0.55

0

0

0

0

Egger's p

0.31

0.39

0.99

0.97

0.65

0.25

0.43

0.51

0.52