From: Somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine tumours, current aspects and new perspectives
Receptor subtype affinity [IC50, nM]
Compound
SSTR1
SSTR2
SSTR3
SSTR4
SSTR5
SMS-14
2.26
0.23
1.43
1.77
0.88
SMS-28
1.85
0.31
1.3
ND
0.4
Octreotide
1140
0.56
34
7030
7
Lanreotide
2330
0.75
107
2100
5.2
Pasireotide
9.3
1
1.5
>100
0.16