Figure 2From: Anti-HER-2 engineering antibody ChA21 inhibits growth and induces apoptosis of SK-OV-3 cellsTransmission electron microscopy observation. After ChA21 (5.4 μg/ml) treatment for 72 h or the tumor tissues removed from nude mice treated ChA21 (40 mg/kg) for 5 weeks, a large number of cells presented a series of ultrastructural changes of apoptosis (B, D). On the contrary, control cells were morphologically normal and exhibited no signals of apoptosis (A, C). (magnification: A, C × 3000; B, D × 8000).Back to article page