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Figure 1 | Journal of Experimental & Clinical Cancer Research

Figure 1

From: Expression and aberrant promoter methylation of Wnt inhibitory factor-1 in human astrocytomas

Figure 1

Selected results of immunohistochemical analysis for anti-human WIF-1 antibodies. Paraffin-embedded sections of representative astrocytomas and normal brain tissues were stained with the antibodies against human WIF-1. The products of WIF-1 expression (brown) located in cytoplasm and membrane. The photographs of A and B are normal brain tissues and pilocytic astrocytoma (WHO grade I)which showed strong staining for WIF-1, respectively. In contrast, the anaplastic astrocytoma(WHO grade III) and glioblastomas(WHO grade IV)that have weak or negative expression levels of WIF-1 were shown in C and D, respectively. Pathological malignancy grade of astrocytoma correlated with IHC score of WIF-1.

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