Table 2 Frequency of PI3KCA mutations found in 264 gastric cancers, by mutation type.
| Â | Mutation | Overall frequency (MSI only) | Percent/total cases | Percent/mutated cases |
|---|---|---|---|---|
Exon 9 | E542K | 2 | 0.76% | 4.76% |
| Â | E545K | 2 | 0.76% | 4.76% |
| Â | Q546K | 4 | 1.52% | 9.52% |
| Â | Total Mutations (ex. 9) | 8 | 3.03% | Â |
Exon 20 | M1043V | 1 | 0.38% | 2.38% |
| Â | H1047R | 26 (8) | 9.85% | 61.90% |
| Â | H1048T | 1 | 0.38% | 2.38% |
| Â | G1050D | 2 | 0.76% | 4.76% |
| Â | T1052I | 1 | 0.38% | 2.38% |
| Â | T1053I | 1 | 0.38% | 2.38% |
| Â | D1056N | 2 | 0.76% | 4.76% |
| Â | L1067F | 1 | 0.38% | 2.38% |
| Â | Total Mutations (ex.20) | 35 | 13.26% | Â |
Total Mutations | Â | 42 | 15.91% | Â |