Table 3 Toxicity for patients treated with pemetrexed plus platinum (n = 53).
Adverse event | Any grade ≥ 1 | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
|---|---|---|---|---|---|
Leucopenia | 26 (49.1) | 10 (18.9) | 11 (20.8) | 3 (5.7) | 2 (3.8) |
Neutropenia | 20 (37.7) | 6 (11.3) | 9 (17.0) | 3 (5.7) | 2(3.8) |
Thrombocytopenia | 17 (32.1) | 11 (20.8) | 2 (3.8) | 2 (3.8) | 2 (3.8) |
Anemia | 8 (15.1) | 4 (7.5) | 4 (7.5) | - | - |
ALT/AST | 3 (5.7) | 3 (5.7) | - | - | - |
Nausea/Vomiting | 26 (49.1) | 16 (30.2) | 9 (17.0) | 1 (1.9) | - |
Diarrhea | 1 (1.9) | - | - | - | 1 (1.9) |
Creatinine | 1 (1.9) | - | - | - | 1 (1.9) |
Pyrexia | 5 (9.4) | 4 (7.5) | 1 (1.9) | - | - |
Fatigue | 10 (18.9) | 10 (18.9) | - | - | - |
Rash | 5 (9.4) | 1 (1.9) | 3 (5.7) | 1 (1.9) | - |
Inflammation | 3 (5.7) | - | 3 (5.7) | - | - |