Skip to main content

Table 3 Genes with changed expression detected after the same combined treatment (ATRA with CA or ATRA with CX) in both cell lines (SK-N-BE(2) and SH-SY5Y)

From: Enhancement of ATRA-induced differentiation of neuroblastoma cells with LOX/COX inhibitors: an expression profiling study

Treatment with ATRA and CA

AKT1, AP2M1, ATF4, CAP1, CCT5, CDK4, CLNS1A, COX6C, COX7A2, GSK3A, HLA-C, HLA-G, KPNA2, LONP1, MAP2K2, MCM2, MSH6, MYBL2, NME1, NME2, PGAM1, PHB2, PKM2, PRKAR1A, PTMA, RAB5A, RET, RHOC, SIVA1, SLC20A1, TBRG4, TSG101, TUFM, UBE2L6, VDAC1, XRCC5, XRCC6

Treatment with ATRA and CX

AP2M1, ATF4, ATP5O, BLMH, CCT5, CDKN1A, CDKN1B, CLNS1A, COX6C, COX7A2, GDF15, HLA-C, HLA-G, HMGA1, HSPB1, LAMB1, LONP1, NQO1, PPARD, PRDX4, RAP1A, RARA, RB1, RET, RHOC, SOD1, TIMP1, TUFM, XRCC5, XRCC6

  1. ATRA was applied in concentrations of 1 or 10 μM (1 ATRA, 10 ATRA); CA in concentrations of 13 and 52 μM (13 CA, 52 CA), and CX in concentrations of 10 and 50 μM (10 CX, 50 CX). The same genes influenced by combinations with both inhibitors are underlined.