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Table 1 Demographics and clinical characteristics of patients with and without constitutively decreased TGFBR1 allelic expression (TGFBR1 ASE).

From: Constitutively decreased TGFBR1 allelic expression is a common finding in colorectal cancer and is associated with three TGFBR1 SNPs

  All patients TGFBR1 ASE + TGFBR1 ASE -
Age, years No % No % No %
Median age 59.5   64.0   59  
Range 35-84   52-77   35-84  
Sex       
Female 55 46.6 4 3.4 51 43.2
Male 63 53.4 7 5.9 56 47.5
Tumor location       
Colon 77 65.3 6 5.1 71 60.2
Rectum 40 33.9 5 4.2 35 29.7
Both 1 0.8 0 0 1 0.8
Ethnic status       
Caucasian 98 83.1 10 8.5 88 7.5
African American 14 11.9 1 0.8 13 11.0
Asian 3 2.5 0 0 3 2.5
Hispanic 3 2.5 0 0 3 2.5
Stage at diagnosis       
Stage 1 11 9.3 1 0.8 10 8.5
Stage 2 30 25.4 5 4.2 25 21.2
Stage 3 44 37.3 1 0.8 43 36.4
Stage 4 33 28.0 4 3.4 29 24.6
Family history       
No 76 64.4 7 5.9 69 58.5
Yes 34 28.8 3 2.5 31 26.3
Unknown 8 6.8 1 0.8 7 5.9