Table 1 Demographics and clinical characteristics of patients with and without constitutively decreased TGFBR1 allelic expression (TGFBR1 ASE).
All patients | TGFBR1 ASE + | TGFBR1 ASE - | ||||
|---|---|---|---|---|---|---|
Age, years | No | % | No | % | No | % |
Median age | 59.5 | 64.0 | 59 | |||
Range | 35-84 | 52-77 | 35-84 | |||
Sex | ||||||
Female | 55 | 46.6 | 4 | 3.4 | 51 | 43.2 |
Male | 63 | 53.4 | 7 | 5.9 | 56 | 47.5 |
Tumor location | ||||||
Colon | 77 | 65.3 | 6 | 5.1 | 71 | 60.2 |
Rectum | 40 | 33.9 | 5 | 4.2 | 35 | 29.7 |
Both | 1 | 0.8 | 0 | 0 | 1 | 0.8 |
Ethnic status | ||||||
Caucasian | 98 | 83.1 | 10 | 8.5 | 88 | 7.5 |
African American | 14 | 11.9 | 1 | 0.8 | 13 | 11.0 |
Asian | 3 | 2.5 | 0 | 0 | 3 | 2.5 |
Hispanic | 3 | 2.5 | 0 | 0 | 3 | 2.5 |
Stage at diagnosis | ||||||
Stage 1 | 11 | 9.3 | 1 | 0.8 | 10 | 8.5 |
Stage 2 | 30 | 25.4 | 5 | 4.2 | 25 | 21.2 |
Stage 3 | 44 | 37.3 | 1 | 0.8 | 43 | 36.4 |
Stage 4 | 33 | 28.0 | 4 | 3.4 | 29 | 24.6 |
Family history | ||||||
No | 76 | 64.4 | 7 | 5.9 | 69 | 58.5 |
Yes | 34 | 28.8 | 3 | 2.5 | 31 | 26.3 |
Unknown | 8 | 6.8 | 1 | 0.8 | 7 | 5.9 |