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Table 2 Association of TGFBR1 SNPs with constitutively decreased TGFBR1 allelic expression (TGFBR1 ASE).

From: Constitutively decreased TGFBR1 allelic expression is a common finding in colorectal cancer and is associated with three TGFBR1 SNPs

  Frequency Allele 2   
SNP ASE < 0.67 or > 1.5 1.5 > ASE > 0.67 P OR
rs4742761 0.14 0.25 0.38 0.5
rs2416666 0.19 0.19 0.98 1.0
rs7874183 0.13 0.28 0.20 0.4
rs7034462 0.31 0.05 7.2 × 10-4 8.3
rs10819634 0.06 0.26 0.08 0.2
rs1888223 0.50 0.30 0.11 2.3
9A/6A 0.31 0.04 1.6 × 10-4 10.9
rs10988705 0.00 0.04 0.42 n/a
rs6478974 0.50 0.47 0.82 1.1
rs10739778 0.38 0.36 0.89 1.1
rs2026811 0.25 0.32 0.57 0.7
rs10512263 0.00 0.11 0.16 n/a
rs11568785 0.25 0.02 1.4 × 10-4 16.0
rs334348 0.31 0.39 0.55 0.7
rs7871490 0.50 0.46 0.77 1.2
rs334349 0.25 0.43 0.19 0.5
rs7850895 0.07 0.06 0.87 1.2
rs1590 0.25 0.39 0.28 0.5
rs1626340 0.25 0.32 0.57 0.7