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Table 2 Univariate analyses of factors associated with recurrence, metastasis and survival

From: Vasculogenic mimicry contributes to lymph node metastasis of laryngeal squamous cell carcinoma

Variable Overall Survival   Disease-Free
Survival
 
  χ2 P χ2 P
Sex, male vs female 1.809 0.179 0.690 0.496
Age, y, ≥60 vs <60 0.075 0.784 0.342 0.559
Tobacco, Yes vs No 2.371 0.124 2.661 0.103
Drink, Yes vs No 0.013 0.911 0.648 0.421
Location,
Super glottic vs glottic vs subglottic
0.585 0.746 6.035 0.049
pTNM stage, Ivs II vs III vs IV 11.600 0.009 4.592 0.204
T classification, T1 vs T2 vs T3 vs T4 10.744 0.013 6.915 0.075
Nodal status, N-positive vs N-negative 6.238 0.013 0.583 0.445
Distant Metastasis, Yes vs No 0.042 0.837 0.374 0.541
Recurrence, Yes vs No 12.386 <0.0001 0.043 0.836
Histopathological grade, 1 vs 2 vs 3 6.529 0.038 1.274 0.529
Tumor size, cm, ≥3 vs <3 4.809 0.028 10.364 0.001
Surgery modality
(cervical neck dissection) Yes vs No
0.672 0.412 1.122 0.290
Radiotherapy, Yes vs No 26.752 <0.0001 27.750 <0.0001
MVD, <17.53 vs ≥17.53 0.084 0.772 0.037 0.847
VM, Yes vs No 6.054 0.014 6.535 0.011
  1. VM: vasculogenic mimicry; MVD: micro vessel density.