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Table 1 Comparisons between Transdermal Fentanyl and Sustained-release Oral Morphine

From: Efficacy and adverse effects of transdermal fentanyl and sustained-release oral morphine in treating moderate-severe cancer pain in Chinese population: a systematic review and meta-analysis

Endpoints

No. of patients/studies

RR (95% CI)a

Pb

Phc

Remission rate

2491/30

1.13 (0.92, 1.38)

0.23

1.00

Constipation

2593/31

0.35 (0.27, 0.45)

< 0.00001

< 0.00001

Nausea/vomiting

2593/31

0.57 (0.49, 0.67)

< 0.00001

0.009

Vertigo/somnolence

2300/28

0.59 (0.51, 0.68)

< 0.00001

0.08

  1. a RR, relative risk; 95% CI, 95% confidence interval
  2. b p value of significance tests of RR = 1
  3. c p value of heterogeneity tests