Endpoints | No. of patients/studies | RR (95% CI)a | Pb | Phc |
---|---|---|---|---|
Remission rate | 2491/30 | 1.13 (0.92, 1.38) | 0.23 | 1.00 |
Constipation | 2593/31 | 0.35 (0.27, 0.45) | < 0.00001 | < 0.00001 |
Nausea/vomiting | 2593/31 | 0.57 (0.49, 0.67) | < 0.00001 | 0.009 |
Vertigo/somnolence | 2300/28 | 0.59 (0.51, 0.68) | < 0.00001 | 0.08 |