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Table 2 Endoscopic findings and grading of radiation colitis in cancer patients receiving external pelvic radiotherapy with or without amifostine prophylaxis.

From: Randomized phase II exploratory study of prophylactic amifostine in cancer patients who receive radical radiotherapy to the pelvis

 

A + R (N = 21)

R (N = 23)

Endoscopically rated colitis

Acute

Late

Acute

Late

Grade 1

-

-

-

2

Grade 2

-

6

2

6

Grade 3

-

1

1

-

Grade 4

-

-

1

-

Totals (%)

-

(0%)+

7

(28,6%)

4

(17,4%)+

8

(34,8%)

  1. *A = Amifostine
  2. **R = Radiotherapy
  3. + p = 0.05