Table 4 Association between gene polymorphisms of hypoxia-related genes and the mean SUVmax in patients with squamous cell carcinoma (n = 78)
Genes | Genotype | SUVmax | P* | Domonant model | SUVmax | P †| Recessive mode | SUVmax | P †|
|---|---|---|---|---|---|---|---|---|---|
SLC2A1 -2841A>T | AA (n = 41) | 9.40 ± 2.63 | 0.155 | AA | 9.40 ± 2.63 | 0.565 | AA + AT | 9.07 ± 2.79 | 0.130 |
|  | AT (n = 29) | 8.60 ± 2.98 |  | AT + TT | 9.04 ± 2.94 |  | TT | 10.64 ± 2.26 |  |
|  | TT (n = 8) | 10.64 ± 2.26 |  |  |  |  |  |  |  |
VEGFA +936C>T | CC (n = 54) | 9.29 ± 2.66 | 0.816 | CC | 9.29 ± 2.66 | 0.774 | CC + CT | 9.20 ± 2.80 | 0.663 |
|  | CT (n = 20) | 8.95 ± 3.23 |  | CT + TT | 9.10 ± 3.06 |  | TT | 9.83 ± 2.25 |  |
|  | TT (n = 4) | 9.83 ± 2.25 |  |  |  |  |  |  |  |
APEX1 Asp148Glu | TT (n = 28) | 8.89 ± 3.04 | 0.522 | TT | 8.89 ± 3.04 | 0.412 | TT + TG | 9.30 ± 2.90 | 0.672 |
|  | TG (n = 34) | 9.64 ± 2.79 |  | TG + GG | 9.43 ± 2.62 |  | GG | 8.97 ± 2.23 |  |
|  | GG (n = 16) | 8.97 ± 2.23 |  |  |  |  |  |  |  |
HIF1A Pro582Ser | CC (n = 69) | 9.32 ± 2.84 | 0.671 |  |  |  |  |  |  |
|  | CT (n = 10) | 8.92 ± 2.35 |  |  |  |  |  |  |  |
HIF1A Ala588Thr | GG (n = 68) | 9.18 ± 2.74 | 0.664 |  |  |  |  |  |  |
|  | GA (n = 10) | 9.59 ± 3.11 |  |  |  |  |  |  |  |