Journal of Experimental & Clinical Cancer Research

Table 2 Dose (Gy) and activity (MBq) relation of ¹⁶⁶Ho treatment

From: Holmium-166 radioembolization for the treatment of patients with liver metastases: design of the phase I HEPAR trial

	Liver weight (kg)
	1	1,5	2	2,5	3
Liver dose (Gy)	A (MBq)	A (MBq)	A (MBq)	A (MBq)	A (MBq)
10	630	945	1260	1575	1890
20	1260	1890	2520	3150	3780
30	1890	2835	3780	4725	5670
40	2520	3780	5040	6300	7560
50	3150	4725	6300	7875	9450
60	3780	5670	7560	9450	11340
70	4410	6615	8820	11025	13230
80	5040	7560	10080	12600	15120

In bold: the four consecutive cohorts receive 1.3 GBq/kg (20 Gy), 2.5 GBq/kg (40 Gy), 3.8 GBq/kg (60 Gy) and 5.0 GBq/kg (80 Gy), respectively. As an example, a patient in the first cohort (20 Gy) with a 1.5-kg liver, will be administered a total activity of 1890 MBq

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ISSN: 1756-9966

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