Relationship and prognostic significance of SPARC and VEGF protein expression in colon cancer

Table 2 Relationship of SPARC expression in colon cancer tissues with clinicopathological parameters

		Tumors cell					MSC
Parameters		low reactivity high reactivity				P value	low reactivity high reactivity				P value
		n	%	n	%		n	%	n	%
Age^a						0.379					0.904
< 59	48	32	66.7	16	33.3		26	54.2	22	45.8
≥ 59	66	49	74.2	17	25.8		35	53.0	31	47.0
Gender						0.276					0.276
men	54	41	75.9	13	24.1		26	48.1	28	51.9
women	60	40	66.7	20	33.3		35	58.3	25	41.7
Tumor size^b						0.222					0.658
< 5.0	52	34	65.4	18	34.6		29	55.8	23	44.2
≥ 5.0	62	47	75.8	15	24.2		32	51.6	30	48.4
Localization						0.140					0.926
colon ascendens	27	22	81.5	5	18.5		14	51.9	13	48.1
flexura hepatica	22	17	77.3	5	22.7		12	54.5	10	45.5
colon transversum	6	6	100	0	0		3	50.0	3	50.0
flexura lienalis	8	6	75.0	2	25.0		3	37.5	5	62.5
colon descendens	6	3	50.0	3	50.0		4	66.7	2	33.3
colon sigmoideum	45	27	60.0	18	40.0		25	55.6	20	44.4
Tumor differentiation						0.930					0.046
low	16	12	75.0	4	25.0		4	25.0	12	75.0
moderate	68	48	70.6	20	29.1		39	57.4	29	42.6
high	30	21	70.0	9	30.0		18	60.0	12	40.0
Lymph node metastasis						0.462					0.013
N0	65	44	67.7	21	32.3		28	43.1	37	56.9
N1	36	26	72.2	10	27.8		22	61.1	14	38.9
N2	13	11	84.6	2	15.4		11	84.6	2	15.4
R/DM^c						0.490					0.746
Yes	23	15	65.2	8	34.8		13	56.5	10	43.5
No	91	66	72.5	25	27.5		48	52.7	43	47.3
L/infiltration^d						0.626					0.678
Yes	41	28	68.3	13	21.7		23	56.1	18	43.9
No	73	53	72.6	20	27.4		38	52.1	35	47.9
depth of invasion						0.459					0.850
T2	15	12	80.0	3	20.0		8	53.3	7	46.7
T3	88	60	68.2	28	31.8		48	54.5	40	45.5
T4	11	9	81.8	2	18.2		5	45.5	6	54.5
Distant metastasis						0.504					0.797
M0	102	71	69.6	31	30.4		55	53.9	47	46.1
M1	12	10	83.3	2	16.7		6	50.0	6	50.0
TNM staging						0.431					0.297
I	11	9	81.8	2	22.2		5	45.5	6	54.5
II	47	30	63.8	17	36.2		21	44.7	26	55.3
III	44	32	72.7	12	27.3		28	63.6	16	36.4
IV	12	10	83.3	2	16.7		7	58.3	5	41.7

ISSN: 1756-9966