Table 3 Genotype and allele frequencies of IL-10 promoter polymorphisms in breast cancer patients and healthy controls
From: Association of interleukin-10 gene polymorphisms with breast cancer in a Chinese population
| Â | Frequency, no.(%) | Â | Â | Frequency, no.(%) | Â | ||
|---|---|---|---|---|---|---|---|
Genetype | Patients n = 315 | Controls n = 322 | P -value | Alleles | Patients 2n = 630 | Controls 2n = 644 | P -value |
-1082 A/G | Â | Â | 0.664 | -1082 A/G | Â | Â | 0.374 |
AA | 285 (90.5) | 285 (88.5) | Â | A | 599 (95.1) | 605 (93.9) | Â |
AG | 29 (9.2) | 35 (10.9) | Â | G | 31 (4.9) | 39 (6.1) | Â |
GG | 1 (0.3) | 2 (0.6) | Â | Â | Â | Â | Â |
-819 T/C | Â | Â | 0.604 | -819 T/C | Â | Â | 0.315 |
TT | 119 (37.8) | 134 (41.6) | Â | T | 373 (59.2) | 399 (62.0) | Â |
TC | 135 (42.9) | 131 (40.7) | Â | C | 257 (40.8) | 245 (38.0) | Â |
CC | 61 (19.3) | 57 (17.7) | Â | Â | Â | Â | Â |
-592 A/C | Â | Â | 0.604 | -592 A/C | Â | Â | 0.315 |
AA | 119 (37.8) | 134 (41.6) | Â | A | 373 (59.2) | 399 (62.0) | Â |
AC | 135 (42.9) | 131 (40.7) | Â | C | 257 (40.8) | 245 (38.0) | Â |
CC | 61 (19.3) | 57 (17.7) | Â | Â | Â | Â | Â |