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Table 2 Univariate analysis for clinicopathologic variables and mRNA expression of VEGF-C

From: Vascular endothelial growth factor C (VEGF-C) in esophageal cancer correlates with lymph node metastasis and poor patient prognosis

parameter

Riskratio

95%aCI

p-value

Primary tumor

   

Tis, T1

1

2.11-16.13

< 0.001

T234

5.85

  

Lymph node metastasis

   

N0

1

1.66-6.9

< 0.001

N1

3.38

  

Lymph Invasion

   

Negative

1

0.98-3.11

0.056

Positive

1.75

  

Vein invasion

   

Negative

1

0.96-2.72

0.067

Positive

1.62

  

VEGF-C expression

   

Low expression

1

1.2-3.4

0.0085

High expression

2.02

  

aCI; confidence interval

   
  1. Univariate analysis shows that, among the clinico-pathological factors, the extent of the primary tumor, lymph node metastasis, and high expression of VEGF-C are all statistically significant prognostic factors