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Table 4 Relationship between clinicopathological factors and mRNA expression of VEGF-C with Tis, T1tumors

From: Vascular endothelial growth factor C (VEGF-C) in esophageal cancer correlates with lymph node metastasis and poor patient prognosis

   

VEGF-C expression

 
  

case

mean

± sd

p-value

age

≧65

8

-0.11

± 0.34

0.15

 

< 65

13

0.12

± 0.33

 

gender

male

19

0.06

± 0.35

0.28

 

female

2

0.25

± 0.24

 

Tfactor

Tis

6

-0.02

± 0.14

0.029

 

T1

15

0.13

± 0.35

 

Nfactor

N0

12

-0.15

± 0.27

 
 

N1

9

0.27

± 0.3

0.003

Stage

Stage0

6

-0.23

± 0.14

 
 

Stage1

6

-0.072

± 0.35

 
 

Stage2A

1

-0.09

  
 

Stage2B

8

0.31

± 0.29

 

Stage0,1 vs Stage2A,2B

   

0.014

Histrogical Type

    
 

well

4

0.45

± 0.18

 
 

moderate

14

-0.1

± 0.29

 
 

poor

3

0.092

± 0.36

 

well · moderate vs poor

   

0.69

lymphatic invasion

    
 

positive

7

0.006

± 0.39

 
 

negative

14

-0.04

± 0.34

0.77

vein invasion

    
 

positive

3

0.053

± 0.51

 
 

negative

18

0.025

± 0.33

> 0.99

  1. The expression of VEGF-C is higher in T1, N1 and Stage2A, 2B tumors than in Tis, N0 and Stage0,1 tumors