Figure 13
From: Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo
Ratio of p-NF-kB/NF-kB in tumors. The xenografts were evaluated for the effects of TQ on NF-κB expression with tumor lysates from xenografts analyzed by western blot for levels of phosphorylated NF-κB as a ratio of total NF-κB. V = Vehicle, TQ = Thymoquinone, C = CDDP at 2.5 mg/kg. Significant reduction in ratio of p NF-κB/NF-κB were seen in xenografts from mice treated with combination of TQ (20 mg/kg) and CDDP (2.5 mg/kg).