Skip to main content

Table 1 Comparison of clinicopathological variables dependent on Snail and Slug mRNA ratios

From: The E-cadherin repressor slug and progression of human extrahepatic hilar cholangiocarcinoma

  Slug mRNA (mean ± SE) P Snail mRNA (mean ± SE) P
mean age (yr)     
<65(15) 86.9 ± 25.5   149.3 ± 57.4  
>65(37) 78.3 ± 19.7 0.1969 171.2 ± 62.8 0.249
Gender     
62.2 ± 32.3 62.2 ± 32.3   127.4 ± 35.6  
70.6 ± 17.5 70.6 ± 17.5 0.2415 124.3 ± 71.8 0.8488
Histologic grading     
G1 (29) 66.4 ± 13.6   107.2 ± 60.2  
G2 (16) 58.0 ± 26.56   114.7 ± 53.5  
G3 (7) 73.2 ± 33.8 0.2523 125.4 ± 41.4 0.7252
Histology     
Well(13) 69.2 ± 18.4   95.7 ± 28.3  
Mod.(27) 76.0 ± 15.8   108.4 ± 46.5  
Poor(12) 85.6 ± 29.2 0.135 100.7 ± 31.1 0.6109
Depth of invasion     
T1(8) 79.2 ± 12.4   117.1 ± 28.0  
T2(32) 68.4 ± 19.7   98.4 ± 34.6  
T3(12) 80.2 ± 30.5 0.1962 109 ± 36.3 0.3260
Surgical margin involvement     
Negative (n = 38) 66.4 ± 16.7   102.6 ± 49.4  
Positive (n = 14) 77.6 ± 31.5 0.2277 124.8 ± 60.0 0.197
Nodal metastasis     
Negative (n = 32) 59.8 ± 23.3   86.8 ± 75.6  
Positive (n = 20) 77.4 ± 22.8 0.0102 109.8 ± 35.2 0.1448
Lymphatic invasion     
Negative (n = 10) 68.3 ± 10.9   180.3 ± 49.4  
Positive (n = 42) 75.6 ± 16.4 0.1404 154. 5 ± 40.1 0.0865
Venous invasion     
Negative (n = 15) 79.6 ± 30.7   120 ± 121.7  
Positive (n = 37) 87.2 ± 24.6 0.3524 134.5 ± 30.6 0.1015
Perineural invasion     
Negative (n = 12) 60.4 ± 16.8   155.2 ± 26.2  
Positive (n = 40) 52.9 ± 14.4 0.134 166.3 ± 40.4 0.3758
Distant metastasis     
Negative (n = 44) 64.8 ± 19.6   163.8 ± 13.6  
Positive (n = 8) 146.3 ± 33.2 0.0001 143.3 ± 27.5 0.0747
Survival (mo)     
<12 (n = 9) 126.8 ± 24.5   176.5 ± 87.2  
>12 (n = 43) 103.3 ± 36.7 0.0443 163.4 ± 54.4 0.5596