Table 1 Comparison of clinicopathological variables dependent on Snail and Slug mRNA ratios

mean age (yr)

<65(15)

86.9 ± 25.5

149.3 ± 57.4

>65(37)

78.3 ± 19.7

0.1969

171.2 ± 62.8

0.249

Gender

62.2 ± 32.3

62.2 ± 32.3

127.4 ± 35.6

70.6 ± 17.5

70.6 ± 17.5

0.2415

124.3 ± 71.8

0.8488

Histologic grading

G1 (29)

66.4 ± 13.6

107.2 ± 60.2

G2 (16)

58.0 ± 26.56

114.7 ± 53.5

G3 (7)

73.2 ± 33.8

0.2523

125.4 ± 41.4

0.7252

Histology

Well(13)

69.2 ± 18.4

95.7 ± 28.3

Mod.(27)

76.0 ± 15.8

108.4 ± 46.5

Poor(12)

85.6 ± 29.2

0.135

100.7 ± 31.1

0.6109

Depth of invasion

T1(8)

79.2 ± 12.4

117.1 ± 28.0

T2(32)

68.4 ± 19.7

98.4 ± 34.6

T3(12)

80.2 ± 30.5

0.1962

109 ± 36.3

0.3260

Surgical margin involvement

Negative (n = 38)

66.4 ± 16.7

102.6 ± 49.4

Positive (n = 14)

77.6 ± 31.5

0.2277

124.8 ± 60.0

0.197

Nodal metastasis

Negative (n = 32)

59.8 ± 23.3

86.8 ± 75.6

Positive (n = 20)

77.4 ± 22.8

0.0102

109.8 ± 35.2

0.1448

Lymphatic invasion

Negative (n = 10)

68.3 ± 10.9

180.3 ± 49.4

Positive (n = 42)

75.6 ± 16.4

0.1404

154. 5 ± 40.1

0.0865

Venous invasion

Negative (n = 15)

79.6 ± 30.7

120 ± 121.7

Positive (n = 37)

87.2 ± 24.6

0.3524

134.5 ± 30.6

0.1015

Perineural invasion

Negative (n = 12)

60.4 ± 16.8

155.2 ± 26.2

Positive (n = 40)

52.9 ± 14.4

0.134

166.3 ± 40.4

0.3758

Distant metastasis

Negative (n = 44)

64.8 ± 19.6

163.8 ± 13.6

Positive (n = 8)

146.3 ± 33.2

0.0001

143.3 ± 27.5

0.0747

Survival (mo)

<12 (n = 9)

126.8 ± 24.5

176.5 ± 87.2

>12 (n = 43)

103.3 ± 36.7

0.0443

163.4 ± 54.4

0.5596