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Table 5 DLCO and FEV1% measured before and at 2 year post-radiotherapy against chemotherapy, TAM and smoking habits.

From: Accelerated hypofractionated radiotherapy as adjuvant regimen after conserving surgery for early breast cancer: interim report of toxicity after a minimum follow up of 3 years

Adverse Event

group

Percentage of ≥G1 grade

p (§)

Percentage of ≥G2 grade

p (§)

DLCO measured before radiotherapy respect to predicted value for each patient

 

Chemotherapy vs no chemotherapy

78% vs. 22%

0.006

38% vs 6%

0.036

 

TAM vs no TAM

43% vs. 44%

0.755

14% vs 17%

0.972

 

Smoking vs no smoking

67% vs. 31%

0.111

44% vs 19%

0.299

DLCO measured at 2 year post-radiotherapy respect to predicted value for each patient

 

Chemotherapy vs no chemotherapy

67% vs. 41%

0.251

45% vs 19%

0.258

 

TAM vs no TAM

44% vs. 52%

0.848

25% vs 29%

0.993

 

Smoking vs no smoking

54% vs. 46%

0.930

31% vs 17%

0.538

FEV1% measured before radiotherapy respect to predicted value for each patient

 

Chemotherapy vs no chemotherapy

40% vs. 42%

0.765

0% vs. 0%

-

 

TAM vs no TAM

36% vs. 43%

0.996

0% vs. 0%

-

 

Smoking vs no smoking

40% vs. 41%

0.882

0% vs. 0%

-

FEV1% measured at 2y-post-radiotherapy respect to predicted value for each patient

 

Chemotherapy vs no chemotherapy

44% vs. 50%

0.890

0% vs. 4%

0.673

 

TAM vs no TAM

44% vs. 56%

0.464

0% vs 6%

0.853

 

Smoking vs no smoking

62% vs. 5%

<0.001

0% vs 5%

0.931

  1. (§) p-value chi-square test