Skip to main content

Table 1 IC50 (μg/ml) for ADM, VCR, Taxol and BLM in 4T1, 4T1/HA117, 4T1/MDR1 and 4T1/GFP cells.

From: Functional study of the novel multidrug resistance gene HA117 and its comparison to multidrug resistance gene 1

 

ADM

VCR

Taxol

BLM

Cell lines

IC50 (μg/ml)

R.I.

IC50 (μg/ml)

R.I.

IC50 (μg/ml)

R.I.

IC50 (μg/ml)

R.I.

4T1

0.4159 ± 0.0791

1

0.4775 ± 0.0757

1

0.0294 ± 0.0058

1

0.4789 ± 0.1104

1

4T1/HA117

**8.2369 ± 1.9458

19.8050

**4.3292 ± 0.4452

9.0663

**0.2859 ± 0.0479

9.7245

*1.7073 ± 0.4062

3.5650

4T1/MDR1

**10.0746 ± 1.0684

24.2236

**5.2754 ± 1.0974

11.0480

**0.3050 ± 0.1067

10.3741

0.4612 ± 0.0733

0.9630

4T1/GFP

0.5126 ± 0.1547

1.2325

0.4508 ± 0.1193

0.9441

0.0292 ± 0.0016

0.9932

0.4924 ± 0.1172

1.0282

  1. Values are shown as the mean ± SD.
  2. ADM: Adriamycin; VCR: vincristine; Taxol: paclitaxel; BLM: bleomycin. * P < 0.05 and ** P < 0.01 compared to the respective control group.