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Table 1 IC50 (μg/ml) for ADM, VCR, Taxol and BLM in 4T1, 4T1/HA117, 4T1/MDR1 and 4T1/GFP cells.

From: Functional study of the novel multidrug resistance gene HA117 and its comparison to multidrug resistance gene 1

  ADM VCR Taxol BLM
Cell lines IC50 (μg/ml) R.I. IC50 (μg/ml) R.I. IC50 (μg/ml) R.I. IC50 (μg/ml) R.I.
4T1 0.4159 ± 0.0791 1 0.4775 ± 0.0757 1 0.0294 ± 0.0058 1 0.4789 ± 0.1104 1
4T1/HA117 **8.2369 ± 1.9458 19.8050 **4.3292 ± 0.4452 9.0663 **0.2859 ± 0.0479 9.7245 *1.7073 ± 0.4062 3.5650
4T1/MDR1 **10.0746 ± 1.0684 24.2236 **5.2754 ± 1.0974 11.0480 **0.3050 ± 0.1067 10.3741 0.4612 ± 0.0733 0.9630
4T1/GFP 0.5126 ± 0.1547 1.2325 0.4508 ± 0.1193 0.9441 0.0292 ± 0.0016 0.9932 0.4924 ± 0.1172 1.0282
  1. Values are shown as the mean ± SD.
  2. ADM: Adriamycin; VCR: vincristine; Taxol: paclitaxel; BLM: bleomycin. * P < 0.05 and ** P < 0.01 compared to the respective control group.