Figure 6
From: Klotho inhibits growth and promotes apoptosis in human lung cancer cell line A549
Influence of down-stream genes expression in klotho-induced apoptosis. (A) After tansfected with MYC-KL, bax and bcl-2 genes transcripts were found up-regulated and down-regulated, respectively. (B) Compared with shRNAc group, bax and bcl-2 genes transcripts were found down-regulated and up-regulated respectively in sh-2/4-transfected group. Data shown are the mean results ± SD of a representative experiment performed in triplicate (n = 3), *indicates p < 0.05; **indicates p < 0.01.