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Figure 4 | Journal of Experimental & Clinical Cancer Research

Figure 4

From: Salivary α-amylase exhibits antiproliferative effects in primary cell cultures of rat mammary epithelial cells and human breast cancer cells

Figure 4

Determinations of α-amylase effects in different cells of human origin. For two HBCEC cultures, a significantly reduced cell number after α-amylase treatment was demonstrated (n = 2-6; mean and SEM). MaCa 700 responded in a dose-dependent manner (a). Additionally, the SA-β-gal assay was performed in MaCa 700 cells, and the proportion of SA-β-gal-positive cells was significantly increased by 125 U/ml α-amylase. The latter parameter showed a tendency for concentration-dependency (Pearson´s correlation coefficient 0.9002; not significant). In MaCa 699 cells, only the lowest concentration caused a significantly decreased cell number (b). Asteriks indicate significant differences vs. control cells (One-way-ANOVA and Bonferroni for selected pairs, p < 0.05).

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