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Table 1 Tumorigenicity of SP Cells in NOD/SCID Xenotransplant Assay

From: Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway

Cells injected/fat pad

Tumors/injections

 

5 × 106

1 × 105

1 × 104

1 × 103

Unsorted

6/6

5/6

5/6

3/6

SP

---

---

6/6

5/6

Non-SP

---

---

5/6

2/6

  1. Table showing the number of tumors generated in NOD/SCID mouse fat pads by SP, non-SP, and unsorted cells. Tumor formation by 1 × 104 cells was observed for 6 weeks after injection, whereas tumor formation by 1 × 103 cells was observed for 9 weeks after injection.