Figure 1

Representative Trop2 immunostain in ovarian and uterine MMT and control normal tissues. Upper left panel: Strong, diffuse membranous Trop2 expression (3+) in the carcinomatous component of ovarian MMT. Upper right panel: Minimal to absent Trop2 expression in normal ovarian surface epithelium and stroma. Lower left panel: Strong, focal membranous Trop2 expression (2+) in the carcinomatous component of uterine MMT. The adjacent sarcomatous component is negative for Trop2. Lower right panel: Weak, focal Trop2 expression in normal endometrial glands. (All images 200× original magnification)