Skip to main content

Advertisement

Table 1 List of the most differentially expressed genes whose changes due to DMH treatment could be reversed by folic acid

From: Folic Acid supplementary reduce the incidence of adenocarcinoma in a mouse model of colorectal cancer: microarray gene expression profile

Accession number Gene symbol Gene Description Fold change P value
Downregulated genes    
NM_207634 Rps24 ribosomal protein S24 (Rps24), transcript variant 2 0.002356454 2.05154E-06
NM_012052 Rps3 ribosomal protein S3 (Rps3) 0.00933479 6.38113E-06
NM_033073 Krt7 keratin 7 0.024674534 0.001286211
NM_024478 Grpel1 GrpE-like 1, mitochondrial (Grpel1) 0.029123617 3.65271E-05
NM_024243 Fuca1 fucosidase, alpha-L- 1 0.031740456 0.000162318
NM_146050 Oit1 oncoprotein induced transcript 1 0.032247549 0.001799574
NM_013614 Odc1 ornithine decarboxylase, structural 1 0.032361 4.48641E-05
NM_025431 Llph LLP homolog, long-term synaptic facilitation (Aplysia) 0.036784284 1.18163E-06
NM_008764 Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b 0.041187965 7.03729E-05
NM_009402 Pglyrp1 peptidoglycan recognition protein 1 0.041272749 0.009299333
NM_010106 Eef1a1 eukaryotic translation elongation factor 1 alpha 1 0.041438052 7.22246E-06
NM_001008700 Il4ra interleukin 4 receptor, alpha 0.043141894 0.000223171
NM_182930 Plekha6 pleckstrin homology domain containing, family A member 6 0.04544609 0.001545018
NM_011463 Spink4 serine peptidase inhibitor, Kazal type 4 0.045587012 0.000688366
NM_016710 Hmgn5 high-mobility group nucleosome binding domain 5 0.046928235 0.000333311
NM_016981 Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 0.052191789 5.29847E-05
NM_145533 Smox spermine oxidase (Smox), transcript variant 2 0.053274908 6.23127E-05
NM_008305 Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.056450624 0.001205571
NM_172051 Tmcc3 transmembrane and coiled coil domains 3 0.058793481 0.001122075
NM_009768 Bsg basigin (Bsg), transcript variant 1 0.061259044 0.000407939
Upregulted genes    
NM_009946 Cplx2 complexin 2 1109.786672 0.000155322
NM_001039493 Plekhm3 pleckstrin homology domain containing, family M, member 3 56.2494337 0.000450001
NM_024272 Ssbp2 single-stranded DNA binding protein 2 (Ssbp2), transcript variant 2 54.215495 2.06403E-05
NM_175013 Pgm5 phosphoglucomutase 5 47.38198278 1.84156E-05
NM_008222 Hccs holocytochrome c synthetase 39.34022581 0.000130923
NM_001033364 Cdhr2 cadherin-related family member 2 38.97741927 0.000749154
NM_023566 Muc2 mucin 2 30.63268666 0.02159023
NM_010418 Herc2 hect domain and RCC1 (CHC1)-like domain (RLD) 2 29.34751955 0.003432199
NM_008261 Hnf4a hepatic nuclear factor 4, alpha 28.66993377 0.000234502
NM_176850 Bptf bromodomain PHD finger transcription factor 26.66298996 0.000156324
  1. Fold change and P values are the results comparing FA3 group and DMH group.